Bioreactor Systems for Human Bone Tissue Engineering
نویسندگان
چکیده
منابع مشابه
Bioreactor Systems for Human Bone Tissue Engineering
Critical size skeletal defects resulting from trauma and pathological disorders still remain a major clinical problem worldwide. Bone engineering aims at generating unlimited amounts of viable tissue substitutes by interfacing osteocompetent cells of different origin and developmental stage with compliant biomaterial scaffolds, and culture the cell/scaffold constructs under proper culture condi...
متن کاملBioreactor systems for bone tissue engineering.
Bone graft material is often required for the treatment of osseous defects. However, due to limitations and risks associated with autologous as well as allogenic bone grafting procedures, alternative strategies are needed. In this context, ex vivo tissue engineering (TE) strategies for de novo generation of bone tissue include the combined use of autologous bone-forming cells and three-dimensio...
متن کاملBioreactor-Based Bone Tissue Engineering
The aim of this chapter is to describe the main issues of bone tissue engineering. Bone transplants are widely used in orthopedic, plastic and reconstructive surgery. Current technologies like autologous and allogenic transplantation have several disadvantages making them relatively unsatisfactory, like donor site morbidity, chronic pain, and immunogenicity and risk hazard from infectious disea...
متن کاملTissue Engineering Bioreactor
pg. 2) Background (pg. 2-8) Alternative Design Descriptions (pg. 8-11) Final Design (pg. 11-13) References (pg. 13) Appendix A: Product Design Specifications (pg. 13-16)
متن کاملSpecial Issue: Design of Bioreactor Systems for Tissue Engineering
Tissue engineering and, more broadly, regenerative medicine is moving into a phase where we are seeing potential therapies moving 'slowly but surely' from the laboratory into the clinic, i.e., from research to the clinic and into manufacturing. The numbers of cells required for cell therapy protocols can vary from tens of millions, to billions [1], and it is widely considered that such cell num...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Processes
سال: 2014
ISSN: 2227-9717
DOI: 10.3390/pr2020494